Spoorthi graduated from Barnard College in 2021 with a Bachelor’s degree in Biochemistry and a minor in Art History. While at Barnard, she completed an honors thesis studying the interaction of proteins implicated in Alzheimer’s disease. She started working with Dr. Chang as a student in 2018 to identify tissue resident memory T cells in synovium samples from patients with rheumatoid arthritis using multispectral microscopy techniques. She then worked on characterizing immune cells in the ocular fluid of patients with autoimmune uveitis. Spoorthi left the Chang lab in 2023 to pursue medical school at UMass T.H. Chan School of Medicine.